Perspective of an OldTime Toxicologist 16An in vitro Test for Teratogens Its Applica 29Teratogenicity Testing of New Drugs with the Postimplanta 46
1. Introduction to experimental toxicology / D.M. Conning2. Effects of physical form, route, and species / A.B. Wilson3. Influence of animal species, strain, age, hormonal, and nutritional status / F.J.C. Roe4. Experimental design / A.B. Wilson5. The biochemical principles of… 더 보기 »Experimental Toxicology
Toxicology — Methods.Cells, Cultured — drug effects.Toxicity testing — In vitro.
CONTENTS AcknowledgementsI IntroductionII Aspects of PainIII Behavior ExperimentsIV CancerV ImmunologyVI Inhalation of Toxic SubstancesVII The Plight of the Nonhuman PrimateVIII RadiationIX Surgical ExperimentsX Tetratogen TestingXI Testing Biological ProductsXII Toxicity Test Procedures for Chemical SubstancesXIII Testing Specific ChemicalsXIV Therapies of Tomorrow
The celebrated naturalist recounts her childhood wish to work with animals and her excursions into the wilds of Africa, where she performed history-making studies on the leopards, lions, and, especially, chimpanzees there.
Man & Beast features some of the greats of Australian literature, writing about the particular kinships they have with animals: the loves, the losses and the surprising turns those relationships can take. Les Carlyon writes about those strange beings, horse… 더 보기 »Man and Beast
A Trre atise on the christian Attitude to The Creatures
1. IntroductIon 9 1.1 Background 9 1.2 objectives and research question 15 1.3 thesis outline 162. theoretIcal background 17 2.1 insights from innovation theory 17 2.2 Lock-in, institutional theory and innovation 193. research desIgn 23 3.1 substituting animal studies in… 더 보기 »Why Animal Studies Are Still Being Used In Drug Development
table of contentsChapter 1 General introduction 7Chapter 2 The ability of animal studies to detect serious post marketingadverse events is limited 17Chapter 3 A retrospective evaluation of non-clinical studies predicting newserious post marketing adverse events of biopharmaceuticals 29Chapter 4 The value of non-human primates… 더 보기 »The Scientific Value of Non-Clinical Animal Studies in drug development